Volume-1, Issue-4

2. Article ID. 0022 : Integrative Medicine Therapies using Natural Remedies in the Management of Type 2 Diabetes 

Authors: Wrushali A. Panchale, Minakshee G. Nimbalwar, Sonam B. Bisen, Gayatri J. Tayade, Jagdish V. Manwar *, Ravindra L. Bakal

Abstract: Diabetes is a chronic fatigue syndrome that happen again when the pancreas does not construct sufficient insulin or when the body cannot constructively use the insulin that it produces. Diabetes and its complications are leading causes of death worldwide, the increased percentage of death worldwide. Type 2 diabetes generally caused by eating wrong foods, lack of sleep, mental stress, toxins, and genetics. Patients with type 2 diabetes look towards natural medicine in addition to their conventional medicine for help in treating their disease.  Natural medicines and using food as medicine is a great way to balance your diabetes treatment. In present article, we have covered information about integrative medicine therapies using natural remedies in the management in type 2 diabetes (diabetes mellitus).

Keywords – Type 2 Diabetes; Diabetes Mellitus; Insulin; Diet.

3. Article ID. 0023 : Newer Approaches in Management of Blood Pressure

Authors: Kanishka Lakhmani,  Aditi Anil Dubey 

Abstract: Blood pressure is one of the important key factors of human body. As per WHO, worldwide 1.13 billion people have high blood pressure, most (two-thirds) living in low- and middle-income countries. In India the prevalence of hypertension is to be 25% in urban and 10% in rural. In India, above age of 60 years, hypertension is more prevalent in females than males and, regardless of Sex, the older the participants were, the more likely they were to have hypertension. Also, Hypertension, a worldwide epidemic at present, is not a disease in itself rather it is a significant risk factor for serious cardiovascular disorders including myocardial infarction, stroke, heart failure, and peripheral artery disease. However, people do suffer from hypotension and shocks which are life-threatening. High and Low blood pressure can be affected, and it can be sometimes lethal if not taken care of at times. Though numerous drugs acting via different mechanism of action are available in the market as conventional formulations for the treatment of hypertension, but they face substantial challenges regarding their bioavailability, dosing and associated adverse effects which greatly limit their therapeutic efficacies.

Keywords – Hypertension, Hypotension, Blood Pressure, Novel drug delivery systems, Nanoparticles, Challenges. 

5. Article ID. 0025: A Comprehensive Findings on SARS-COV-19 Virus

Authors: Kajal D. Chaudhari, Jagdish V. Manwar, Ravindra L. Bakal, Rahul D. Jawarkar, Chetan M. Jain,  Snehal S. Manekar

Abstract: SARS-CoV-2 is one amongst the various styles of coronavirus; these viruses are known to cause illnesses which range from a typical cold to a more severe respiratory disorder. The infection began to spread from the Human seafood wholesale market in Wuhan, China, while the precise infection route of the primary case remains unclear. As of September 4th 2020, the etiologic agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread all over the world, leading to around 26 million confirmed cases and around 865,000 deaths. The disease is transmitted by inhalation or contact with infected droplets and the incubation period ranges from 2 to 14 d. The symptoms are usually fever, cough, sore throat, breathlessness, fatigue, malaise among others. The antiviral drugs, including Oseltamivir, ribavirin, ganciclovir, lopinavir, and ritonavir have been used in attempts to reduce viral load and to prevent the likelihood of respiratory complications in several studies. Chloroquine and Remdesivir effectively controlled the COVID-19 infection in in-vitro cell culture. The University of Oxford developed a vaccine supported Chimpanzee Adenovirus Vector (ChAdOx1) which is immunogenic in mice. The vaccine candidate entered phase I/II (NCT04324606) trial in April 2020 to check its safety, tolerability, and immunogenicity in 510 volunteers. The protective efficacy and the short term and long-term side effects of vaccine are of major concern.

Keywords – SARS-CoV-2; droplet infection; Chloroquine; Remdesivir.